Pricing & Availability
- Clone
- 1-21 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- T-cell leukemia/lymphoma protein 1A, Protein p14 TCL1, Oncogene TCL1, TCL-1
- Isotype
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes stained with anti-CD19 (HIB19) APC then intracellularly stained with 1-21 PE
Compare all formats See PE spectral data
Input string was not in a correct format.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 330506 | 100 tests | $270.00 | ||||
Description
Product Details
Technical data sheet
Product Details
- Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- outer α-loop region of TCL1 peptide
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
- ICFC – Quality tested
- Recommended Usage
- Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm) - Application Notes
- Additional reported applications include: immunoprecipitation, western blot, immunohistochemical staining of frozen or formalin-fixed, paraffin embedded tissue sections.
- Application References(PubMed link indicates BioLegend citation)
-
- Herling M, et al. 2008. Blood 111:328
- Herling M, et al. 2007. Am. J. Surg. Pathol. 31:1123
- Product Citations
-
- Kubota S, et al. 2019. Nat Commun. 10:1653. PubMed
- O’Connor T, et al. 2020. Cancer Cell. 36(3):250-267. PubMed
- RRID
- AB_2204407 (BioLegend Cat. No. 330506)
Antigen Details
- Structure
- Beta barrel protein, 14kD
- Distribution
- Cytoplasm
- Function
- Enhances Akt mediated cell survival, stabilizes mitochondrial membrane potential
- Interaction
- Akt1, Akt2, Akt3, caco2
- Biology Area
- Cell Biology, Immunology
- Molecular Family
- CD Molecules
- Antigen References
- 1. Narducci MG et al. 2000. Cancer Research 60:2095.
2. Teitell MA et al. 2005 Nat. Rev. Cancer 5:640
3. Laine J et al.2000. Molecular Cell 6:395
4. Virgilio L et al. 1994. Proc. Natl. Acad. Sci. 91:12530
5. Masayuk N et al. 2007 FASEB J. 21:2273
6. Despouy G et al. 2007 Blood 110:4406
7. Rhine S et al. 2006 Blood 108:1991 - Gene ID
- 8115 View all products for this Gene ID
- UniProt
- View information about TCL1 on UniProt.org
Related Products
| Description | Clone | Applications |
|---|
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All TCL1 Reagents Request Custom Conjugation
| Description | Clone | Applications |
|---|---|---|
| Alexa Fluor® 647 anti-human TCL1 | 1-21 | ICFC |
| PE anti-human TCL1 | 1-21 | ICFC |