Dojindo,胺反应性PES/10/A543

Product Description

胺反应性 PES 是一种新型的氨基反应性电子介体。 该介体可以通过共价键与葡萄糖脱氢酶等酶连接，有望应用于下一代生物传感器。

新一代电子介体通过用胺反应性PES修饰酶，与酶表面结合的介体能够将电子从还原的辅因子转移到电极。 该传感系统可用于减少电极的介体泄漏和替代昂贵的金属络合物。

Modification of enzymes using Amine-reactive PES is patent pending.

Electrochemical Measurement of Glucose

The concentration of glucose was measured by modifying enzyme using arPES and this sensing system has the potential to develop continuous monitoring for various target molecules such as glucose.

The Sensing System is Applicable to the Following Enzymes– FAD-dependent glucose dehydrogenase (FAD-GDH)– L-Lactate oxidase (Lox)– Fructosyl amino acid oxidase (FAOx)– Cholesterol oxidase (ChOx)– Pyranose oxidase (PyOx)

Procedure for PES-modification

Easy procedure: Just mix enzyme and amine-reactive PES

M. Hatada, N. Loew, Y. Takahashi, J. Okuda-Shimazaki, W. Tsugawa, A. Mulchandani, K. Sode. ” Development of a glucose sensor employing quick and easy modification method with mediator for altering electron acceptor preference.” Bioelectrochemistry, 2018, 121, 185.