Dojindo,11-AUPA/100/A517,氧化钛膜上形成 11-HUPA 的 SAM 以修饰荧光分子

2022年4月24日 作者 jinpanbio
膦酸衍生物用于氧化金属如Al2O31)、TiO22)、ZrO23)、SiO24)、Mica5)、不锈钢(SS316L)6)、镍钛诺7)、羟基磷灰石8)、ZnO9)、ITO10、11)的表面改性。长期以来,有机硅烷被用于在金属氧化物上形成自组装单分子层(SAM)。然而,由于试剂之间的稳定性和聚合性差,在应用中并不总是适用。另一方面,膦酸衍生物同样在金属氧化物上形成SAM,尽管它们是非常稳定的化合物。此外,据报道,膦酸衍生物使用形成比有机硅烷更稳定和致密的 SAM。施瓦茨等。人。表明当在氧化钛膜上形成 11-HUPA 的 SAM 以修饰荧光分子时,膦酸盐 SAM 在碱性溶液中的稳定性和密度是有机硅烷的四倍。膦酸衍生物机械地结合到氧化钛膜上的高密度,因为膦酸衍生物通过质子转移到基材产生 OH,而有机硅烷仅与氧化钛膜中存在的 OH 基团反应12)。

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