lonza CC-2932,原代细胞和干细胞,D-SAEC-As患病的小气道上皮细胞 – 哮喘

2022年4月1日 作者 jinpanbio
Catalog #: CC-2932
D-SAEC-As, Small Airway Epithelial Cells, Asthma

Product Overview

哮喘是一种气道炎症性疾病,可导致患者出现喘息、气短、胸闷和咳嗽。严重程度因个体患者而异,对药物治疗的反应也是如此。嗜酸性粒细胞与支气管上皮细胞的粘附以及气道平滑肌和上皮下成纤维细胞的相互作用在哮喘病理学中起关键作用。在哮喘发作期间,细支气管平滑肌组织可以收缩和减少气道中的空气流动。炎症或粘液分泌过多可进一步减少气流量。

细胞角蛋白染色的小气道上皮细胞 19. Lonza 的人小气道上皮细胞 (SAEC) 是从 1mm 细支气管区域肺远端部分的哮喘人肺组织中分离出来的。

来自哮喘供体的冷冻保存的 SAEC 通过 15 次群体倍增和细胞角蛋白染色阳性 19 得到保证。所有细胞的支原体、细菌、酵母和真菌检测均为阴性。并非所有供体和/或细胞批次都检测到 HIV-1、乙型肝炎和丙型肝炎。为每个购买的细胞批次提供一份分析证书。

Applications

  • Gene expression pathways
  • Phenotypic changes to compounds
  • Transfect diseased cells
  • Co-culture with immune cells
  • Airway remodeling studies
  • Cellular interactions

Content & Storage

Content

1 x Cryopreserved Ampule with ≥500,000 cells/vial

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